Season
- Season 16 2008-09-02
- Season 15 2007-09-04
- Season 14 2006-09-05
- Season 13 2005-09-06
- Season 12 2004-08-31
- Season 11 2003-09-03
- Season 10 2002-09-03
- Season 9 2001-09-04
- Season 8 2000-09-05
- Season 7 1999-09-07
- Season 6 1998-09-15
- Season 5 1997-09-09
- Season 4 1996-09-17
- Season 3 1995-09-11
- Season 2 1994-09-12
- Season 1 1993-09-13
- Season 0 1998-09-16
Episode
- Episode 1: David Duchovny, Tim Gunn, Kevin Brennan
- Episode 2: Clive Owen, Alan Alda, Dinosaur Jr.
- Episode 3: Will Arnett, Terry Crews, Patti Scialfa
- Episode 4: Jeff Garlin, Nicholas Art, Hot Hot Heat
- Episode 5: Paul Giamatti, Alyson Hannigan, Bad Religion
- Episode 6: Richard Gere, Seann William Scott, The Chesterfield Kings
- Episode 7: Mary-Kate Olsen, Wayne Brady, Lyle Lovett
- Episode 8: Billy Bob Thornton, Sen. Chris Dodd, Kenny Chesney
- Episode 9: Patricia Heaton, Tiki Barber, The Used
- Episode 10: Morgan Freeman, Cheryl Hines, KT Turnstall
- Episode 11: Kelsey Grammer, Aries Spears, James Blunt
- Episode 12: Brad Garrett, Joy Behar, Rogue Wave
- Episode 13: Terrence Howard, Simon Pegg, Mystery
- Episode 14: Meredith Vieira, Steven Wright, Ben Harper & the Innocent Criminals
- Episode 15: Bob Costas, Jim Gaffigan, Rilo Kiley
- Episode 16: Jamie Foxx, Heather Graham, Mike Birgbiglia
- Episode 17: Ted Danson, Patton Oswalt, Devendra Banhart
- Episode 18: Dwayne "The Rock" Johnson, Ed Helms, Bjork
- Episode 19: Seth Meyers, Bret Michaels, Jose Gonzalez
- Episode 20: Jerry O'Connell, Ken Burns, VHS or Beta
- Episode 21: Ted Koppel, Jason Schwartzman, Dana Gould
- Episode 22: Tina Fey, Kenneth Branagh, Ani DiFranco
- Episode 23: Snoop Dogg, Connie Britton, Bloc Party
- Episode 24: Jennifer Connelly, Fred Willard, Animal Collective
- Episode 25: Joaquin Phoenix, Jim Gaffigan, Paramore
- Episode 26: Mark Wahlberg, Michael Strahan, The Black Lips
- Episode 27: Tracy Morgan, Emile Hirsch, A.J. Jacobs
- Episode 28: Jon Bon Jovi, Eva Mendes, Klaxons
- Episode 29: Anderson Cooper, Paget Brewster, Fionn Regan
- Episode 30: Jake Gyllenhaal, Christina Hendricks, Ghostland Observatory
- Episode 31: Anthony Hopkins, Joe Buck, Mute Math
- Episode 32: John Cusack, James Lipton, Spoon
- Episode 33: Josh Harnett, Jack McBrayer, Brother Ali
- Episode 34: Charles Barkley, William Baldwin, Seether
- Episode 35: Ethan Hawke, Susie Essman, Zappa Plays Zappa
- Episode 36: Brian Williams, Roger Daltrey, Manchester Orchestra
- Episode 37: Dane Cook, Emily Mortimer, Slash
- Episode 38: Jerry Seinfeld, David Ortiz, Sondre Lerche
- Episode 39: Bob Saget, Dwayne Perkins, Robert Gordon & Chris Spedding
- Episode 40: Megan Mullally, Fonzworth Bentley, Kid Rock
- Episode 41: Bill Maher, Jim Cramer, Mike Destefano
- Episode 42: Hulk Hogan, Regina Hall, Nicole Atkins & the Sea
- Episode 43: Donald Trump, Irina Markova and her performing dogs, Sia
- Episode 44: Ice Cube, Dr. Drew Pinsky, Marah
- Episode 45: Howie Mandel, Leigh Killian, Kate Nash
- Episode 46: Brian Williams, David Wondrich, Doyle & Debbie
- Episode 47: Lester Holt, Sue Johanson, Ingrid Michaelson
- Episode 48: Tom Brokaw, Anthony Jeselnik, Bell X1
- Episode 49: Pink, Lou Dobbs, Bettye LaVette
- Episode 50: Chazz Palminteri, Erin Burnett, Louis XIV
- Episode 51: Bret Michaels, Antonio Pierce, Lisa Loeb
- Episode 52: Jim Gaffigan, Chuck Liddell, Joe Nichols
- Episode 53: David Gregory, Travis Pastrana, Kate Walsh
- Episode 54: Jeff Corwin, Colin Hanks, Matt Nathanson
- Episode 55: Dr. Phil McGraw, David Borgenicht, Les Savy Fav
- Episode 56: Shawn Thayer, Ingrid Backstrom, The Blind Boys of Alabama
- Episode 57: Ann Curry, Mike Epps, OneRepublic
- Episode 58: Michael Strahan, Sarah Bolger, Sheryl Crow
- Episode 59: The Great Throwdini, Donny Deutsch, The Dillinger Escape Plan
- Episode 60: Izabel Goulart, Len Berman, Nada Surf
- Episode 61: Professor Peter H. Fisher, Dr. Bob Arnot, Eric Lindell
- Episode 62: Carson Kressley, Jim DeRogatis & Greg Kot, Catherine Russell
- Episode 63: Jim Cramer, José Andrés, Band of Horses
- Episode 64: Matt Lauer, Ryan Reynolds, Simple Plan
- Episode 65: Martin Short, Ray Allen, The Kooks
- Episode 66: Neil Patrick Harris, Daniella Sarahyba, Yeasayer
- Episode 67: Larry the Cable Guy, Tim Gunn, Jim Lauderdale
- Episode 68: Anderson Cooper, Bill Hader, Jake Shimabukuro
- Episode 69: Randy Jackson, Artie Lange, The Whigs
- Episode 70: Barbara Walters, Wladimir Klitschko, Black Mountain
- Episode 71: Nathan Lane, Michel Gondry, Secondhand Serenade
- Episode 72: Will Arnett, Flavor Flav, Super Furry Animals
- Episode 73: Will Ferrell, Rashida Jones, tae kwon do expert Fred Simmons
- Episode 74: Tom Arnold, Todd Barry, Georgie James
- Episode 75: Natalie Portman, Robert Schimmel, James Blunt
- Episode 76: Christina Ricci, Jason Sudeikis, Shooter Jennings
- Episode 77: Paul Giamatti, Mark 'Dr. Bugs' Moffett, Jaymay
- Episode 78: Jonah Hill, John Tesh, Drive-By Truckers
- Episode 79: Snoop Dogg, Carson Daly
- Episode 80: Meredith Vieira, Harland Williams, Keith Robinson
- Episode 81: Frank Caliendo, Cheryl Hines, The Bad Plus
- Episode 82: Martha Stewart, Lance Krall, Billy Bragg
- Episode 83: Ice-T, Brian Posehn, Stars
- Episode 84: Tracy Morgan, Chris Hansen, Paul Thorn
- Episode 85: David Schwimmer, Drake Bell, Yael Naim
- Episode 86: Ryan Phillippe, Big Show, JB Smooth
- Episode 87: Bob Costas, Marc Maron, Moby
- Episode 88: Helen Mirren, yodeler Wylie Gustafson, Carbon/Silicon
- Episode 89: John Leguizamo, George Takei, The Bravery
- Episode 90: John Krasinski, Bode Miller, Cobra Starship
- Episode 91: Christina Applegate, Lewis Black, Stephen Curry
- Episode 92: George Wendt, Howard Bach, Hot Chip
- Episode 93: Jarod Miller, David Gregory, John Oliver
- Episode 94: Eddie Izzard, Morgan Spurlock, Tapes 'N Tapes
- Episode 95: Sarah Jessica Parker, Eddie Izzard, They Might Be Giants
- Episode 96: Patrick Stewart, Oliver Hudson, A.A. Bondy
- Episode 97: Rachael Ray, Kal Penn, Grizzly Bear
- Episode 98: Andy Richter, Jennifer Esposito, She + Him
- Episode 99: Seth Green, Peter Greenberg, Radiohead
- Episode 100: Amy Poehler, Danica Patrick, Dave Attell
- Episode 101: Tina Fey, Fred Willard, Say Anything
- Episode 102: Marisa Tomei, Anthony Anderson, Santogold
- Episode 103: Jeff Garlin, Dax Shepard, The Kills
- Episode 104: Gordon Ramsay, Rob Corddry, Feist
- Episode 105: Sigourney Weaver, Darrell Hammond, Was (Not Was)
- Episode 106: Matthew Broderick, Michelle Monaghan, Brian Turner
- Episode 107: Patricia Heaton, Katt Williams, Thrice
- Episode 108: Jason Lee, Eva Amurri, Galactic
- Episode 109: Liam Neeson, B.J. Novak, The Duke Spirit
- Episode 110: Emile Hirsch, Terrell Owens, Craig Baldo
- Episode 111: Seth Meyers, Sophia Bush, Tokio Hotel
- Episode 112: Jimmy Fallon, William Shatner, Gary Vaynerchuk
- Episode 113: Steve Carell, Alyson Hannigan, Duffy
- Episode 114: Brian Williams, Leighton Meester, The Black Keys
- Episode 115: Seth MacFarlane, Carlos Mencia, MGMT
- Episode 116: Alan Alda, John Cena, Everest
- Episode 117: Kevin Nealon, Mary McCormack, DeVotchKa
- Episode 118: Denis Leary, Anthony Bourdain, Mates of State
- Episode 119: Harrison Ford, Eric McCormack, Atmosphere
- Episode 120: Kevin Spacey, Cynthia Nixon, Brian Kiley
- Episode 121: Kristin Davis, Ira Glass, Ryan Bingham
- Episode 122: The Strike Beard Show
- Episode 123: Jon Bon Jovi, Eva Mendes
- Episode 124: Seann William Scott, Tim Meadows, The Raconteurs
- Episode 125: Colin Firth, Hugh Rowland, Jackie Greene
- Episode 126: Adam Sandler, Werner Herzog, Jewel
- Episode 127: Wanda Sykes, Emmanuelle Chriqui, Lewis Black
- Episode 128: Kim Cattrall, Matt Taibbi, Lightspeed Champion
- Episode 129: Kate Hudson, Robert Smigel, James Hunter
- Episode 130: Jeff Corwin, Mario Lopez, Jamie Lidell
- Episode 131: Mark Wahlberg, Louis C.K., Sharon Jones and The Dap-Kings
- Episode 132: Randy Jackson, Piper Perabo, Forever the Sickest Kids
- Episode 133: Michael Strahan, D.L. Hughley, Brian Scolaro
- Episode 134: Ann Curry, Mario Batali, The Lordz
- Episode 135: Megan Mullally, Brittany Snow, Detroit Octane
- Episode 136: Mike Myers, Jordana Spiro, Dolphina
- Episode 137: Anne Hathaway, Romany Malco, My Morning Jacket
- Episode 138: Jason Bateman, Masi Oka, Alejandro Escovedo
- Episode 139: Ted Koppel, Emily Mortimer, Steel Train
- Episode 140: Selma Blair, Sig Hansen, Little Jackie
- Episode 141: Kyra Sedgwick, Jim Cramer, Joe Cocker
- Episode 142: Al Roker, Paul Pierce, Pilobolus
- Episode 143: Sean Hayes, Ed Helms, Tom Papa
- Episode 144: Gary Oldman, Joe Buck, Kenny Chesney
- Episode 145: Heidi Klum, Joel McHale, Daryl Hall & K.T. Tunstall
- Episode 146: Seth Green, Russell Brand, Eugene Mirman
- Episode 147: Aaron Eckhart, Caroline Rhea, Dr. Dog
- Episode 148: Senator John McCain and The Steeldrivers
- Episode 149: Carson Kressley, Keke Palmer, The Ting Tings
- Episode 150: Jason Sudeikis, Dr. Wladimir
- Episode 151: Kevin Costner, Maria Bello, Yuto Miyazawa & Gogol Bordello
- Episode 152: Nathan Lane, Dylan Ratigan, Missy Higgins
- Episode 153: Brendan Fraser, Steve Schirripa, The Airborne Toxic Event
- Episode 154: America Ferrera, Judd Apatow, Dwayne Perkins
- Episode 155: Seth Meyers, Sharon Osbourne, N*E*R*D
- Episode 156: Javier Bardem, Danny McBride, The B-52s
- Episode 157: Seth Rogen, Philippe Petit, Al Green
- Episode 158: Kiefer Sutherland, Jim Gaffigan, Mason Jennings
- Episode 159: Daniel Radcliffe, Steve Coogan, The Hold Steady
- Episode 160: Vin Diesel, Dave Attell, The Virgins
- Episode 161: Tiger Woods, Vanessa Minnillo, Jimmy Carr
- Episode 162: Aaron Peirsol, Anthony Anderson, Lykke Li
- Episode 163: Bob Costas, Sophia Bush, The Spring Standards
Late Night with Conan O'Brien Season 15 Patrick Stewart, Oliver Hudson, A.A. Bondy
Stepping into the late-late slot vacated by David Letterman, Conan O'Brien stars in a show that far outdoes its competition in sheer strangeness. Along with the celebrity interviews and musical numbers typical of late-night talk shows, this program make frequent use of odd walk-on characters and frequent "visits" from celebrity guests.
